Domino's Pizza - Port Isabel

1702 State Highway 100 Ste D

Port Isabel, Texas 78578 | (956) 943-8880
  • Mon-Thu: 10:30 am to 12 am
  • Fri-Sat: 10:30 am to 1 am
  • Sun: 10:30 am to 12 am
Get Directions

FREE COUPONS Sign up and never miss a deal!

Pizza Coupons Near You

Exclusive Online Offers

More About Domino's on State Highway 100

Domino's: We're Reinventing Pizza at 1702 State Highway 100

When your stomach starts talkin' and your tastebuds start tinglin' for a classic slice of meaty, cheesy goodness, we know you're not craving any old pizza in Port Isabel You want a hot, delicious pizza with a flavorful tomato sauce, perfectly sliced bits of pepperoni, generous piles of mozzarella and parmesan, and a crust that's both crunchy and chewy—all at the same time. You want only the best pizza. You want Domino's.

At Domino's on State Highway 100, it's never been easier to get the fast and delicious pizza your stomach is grumbling for! Visit us in person to place a takeout order, call (956) 943-8880, or order your pizza online!

Start by choosing from one of our handmade crusts, including a fluffy hand-tossed crust loaded with buttery flavor, a crispy thin crust, a pan crust featuring two delicious layers of cheese, or even a gluten-free pizza crust! And next, select your sauce and start loading up on toppings. Pick as many or as few as you want! Whether you want to combine sausage, bacon, salami and green peppers, or stick to a blend of cheddar, mozzarella, feta, and asiago cheese, you can count on your local Domino's to deliver.

We've got slices to suit any taste. How do we know? Because there are more than 34 million ways to craft a single Domino's pizza. Customize your pizza from bottom to top or choose from one of our chef-inspired specialty pizzas, like the ever popular Ultimate Pepperoni, MeatZZa™, or Cali Chicken Bacon Ranch, and have it delivered hot and fresh to your doorstep, today!

Like A Butler, But For Pizza: Port Isabel Pizza Delivery Near State Highway 100

When it comes to pizza delivery, we take things pretty seriously at your local Domino's on State Highway 100. In fact, we guarantee your pizza will arrive hot and fresh, right from our oven to your door. Want to see how fast we can deliver? After you place your order, use our patented TrackerⓇ to stay up to date on the status of your pizza order. Follow it from the moment the sauce is added to the second it leaves our door for delivery... and do your best not to drool on your computer's keyboard in the meantime.

Order online or call (956) 943-8880 for fast, fresh, and easy pizza delivery from Domino's! Trust us. Your tastebuds will seriously appreciate it!

Nearby Points of Interest


  • SAT

High Schools

  • Port Isabel High School