Domino's Pizza - Houston

21129 State Highway 249

Houston, Texas 77070 | (281) 251-2100
  • Mon-Thu: 10 am to 12 am
  • Fri-Sat: 10 am to 1 am
  • Sun: 10 am to 12 am
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More About Domino's on State Highway 249

Domino's: We're Reinventing Pizza at 21129 State Highway 249

When your tastebuds are tingling for a delicious slice of cheesy, meat-topped goodness, we know you're not craving any old pizza in Houston. You're looking for a delectable pizza with a freshly made tomato sauce, a hearty blend of mozzarella and parmesan, expertly diced bits of pepperoni, and a golden-brown crust that's both crispy and chewy. You want an undeniably good pizza. You want Domino's.

At Domino's on State Highway 249, it's never been easier to get the fast and delicious pizza your stomach is grumbling for! Walk in to place a takeout order, order your pizza online, or give us a call at (281) 251-2100!

First, start by selecting your favorite crust. Pick from a hand-tossed crust that's seasoned with garlic and butter, a pan crust featuring two colossal layers of cheese, a crunchy thin crust, or even a gluten-free pizza crust! And next, select your sauce and start loading up on toppings. Pick as many or as few as you want! Whether you're all about the veggies like green peppers, spinach, and onions, or you prefer the sweet and savory combination of ham and pineapple, you can count on your local Domino's to deliver.

With more than 34 million different ways to handcraft a Domino's pizza, you can be sure we've got a slice for whatever your tastebuds are craving. Customize your pizza from bottom to top or choose from one of our chef-inspired specialty pizzas, like the ever popular Buffalo Chicken, Pacific Veggie, or Ultimate Pepperoni and have it delivered hot and fresh to your doorstep, fast!

From Our Oven on State Highway 249 to Your Door: Houston Pizza Delivery

At your Domino's on State Highway 249, we don't take pizza delivery lightly. We guarantee that your pizza will arrive at your doorstep hot and fresh, straight from our oven. Use our patented Pizza TrackerⓇ to follow the progress of your pizza order from the time it's placed till it arrives at your doorstep… and try to keep your drool from falling onto your keyboard or phone in the meantime.

Don't keep your hunger waiting any longer! Call (281) 251-2100 or click to order pizza delivery from Domino's now!

Nearby Points of Interest


  • IAH

High Schools

  • Cypress Creek High School


  • Houston Methodist Willowbrook Hospital