Domino's Pizza - Duncan

2153 E Main St

Duncan, South Carolina 29334 | (864) 485-2333
  • Mon-Thu: 10:30 am to 12 am
  • Fri-Sat: 10:30 am to 1 am
  • Sun: 10:30 am to 12 am
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More About Domino's on Main St

Order Pizza at 2153 E Main St: Tasty & Fresh From the Oven!

When you're craving a mouthwatering slice of cheesy, meaty goodness, we know you're not craving just any old pizza in Duncan. You're looking for a delectable pizza with a freshly made tomato sauce, a hearty blend of mozzarella and parmesan, expertly diced bits of pepperoni, and a golden-brown crust that's crunchy, crispy, and chewy—all at the same time. You want pizza, perfected. You want Domino's.

At Domino's on Main St, it's never been easier to get the fast and fresh pizza your tastebuds are begging you for! Visit us in person to place a takeout order, call (864) 485-2333, or order your pizza online!

Start by choosing from one of our handmade crusts, including a fluffy hand-tossed crust loaded with buttery flavor, a crispy thin crust, a pan crust featuring two delicious layers of cheese, or even a gluten-free pizza crust! Then, choose a sauce and pile on as many or as few toppings as you want. Whether you're a serious fan of mushrooms and spinach or love spicy pepperoni and tangy asiago cheese, you can be sure your local Domino's has it all.

There are over 34 million ways to craft a single Domino's pizza. That means you can be sure we've got a slice for whatever your hunger demands! Build your own pizza however you want or choose from one of our beloved specialty pizzas, like the popular Spinach and Feta, Cali Chicken Bacon Ranch, or MeatZZa™, and have it delivered to your doorstep, today!

Fast Pizza Delivery on Main St in Duncan

Here at your Domino's on Main St, we're serious about pizza delivery. In fact, we guarantee your pizza will arrive hot and fresh, right from our oven to your door. Can't wait for your pie to arrive? Use our patented Pizza TrackerⓇ system and follow your pizza order as it's prepped, baked, and headed out the door for delivery... and do your best not to drool on your computer's keyboard in the meantime.

Order online or call (864) 485-2333 for fast, fresh, and easy pizza delivery from Domino's! Trust us. Your tastebuds will seriously appreciate it!