Domino's Pizza - Columbus

6144 E Main St

Columbus, Ohio 43213 | (614) 860-0030
  • Mon-Thu: 10 am to 12 am
  • Fri-Sat: 10 am to 1 am
  • Sun: 10 am to 12 am
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More About Domino's on Main St

Order Fresh Handcrafted Pizza at 6144 E Main St

When you're craving a mouthwatering slice of cheesy, meaty goodness, we know you're not craving just any old pizza in Columbus. You're looking for a delectable pizza with a freshly made tomato sauce, perfectly diced pepperoni, heaping piles of mozzarella cheese, and a golden-brown crust that's both crispy and chewy. You want only the best pizza. You want Domino's.

At Domino's on Main St, we make it easy to get exactly what you want: pizza that's fast and fresh. Stop by to place a takeout order, order your pizza online, or give us a call at (614) 860-0030!

Get started by selecting your favorite crust. Choose from a hand-tossed crust that's overflowing with buttery flavor, a gluten-free crust, a pan crust featuring two monstrous layers of cheese, or even a crispy thin pizza crust! Next, pick your sauce and load up on your favorite, most delish toppings. Whether you want to combine sausage, bacon, salami and green peppers, or stick to a blend of cheddar, mozzarella, feta, and asiago cheese, your pizza dreams can come true at your local Domino's.

With over 34 million different ways to make a single Domino's pizza, you can be sure we've got a slice for any taste. Build your own pizza however you want or choose from one of our beloved specialty pizzas, like the popular MeatZZa™, Honolulu Hawaiian, or Memphis BBQ Chicken, and have it delivered to your door today, fast!

Fast Pizza Delivery on Main St in Columbus

Here at your Domino's on Main St, we're serious about pizza delivery. In fact, we promise your pizza will arrive hot and fresh at your door, right out of our oven. Use our patented Pizza TrackerⓇ to follow the progress of your pizza order from the time it's placed till it arrives at your doorstep… and try not to drool on your keyboard while you wait.

Order online or call (614) 860-0030 for fast, fresh, and easy pizza delivery from Domino's! Trust us. Your tastebuds will seriously appreciate it!

Nearby Points of Interest


  • CMH

High Schools

  • Eastmoor Academy


  • Mount Carmel East