Domino's Pizza - Patchogue

232 E Main St

Patchogue, New York 11772 | (631) 207-6800
  • Mon-Thu: 10:30 am to 1 am
  • Fri-Sat: 10:30 am to 2 am
  • Sun: 10:30 am to 1 am
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More About Domino's on Main St

Order Pizza at 232 E Main St: Tasty & Fresh From the Oven!

When your stomach starts talkin' and your tastebuds start tinglin' for a classic slice of meaty, cheesy goodness, we know you're not craving any old pizza in Patchogue You want a hot, delicious pizza with a flavorful tomato sauce, perfectly diced pepperoni, heaping piles of mozzarella cheese, and a crust that's both crunchy and chewy—all at the same time. You want an undeniably good pizza. You want Domino's.

At Domino's on Main St, we make it fast and easy to get the fresh pizza you're craving. Call (631) 207-6800 to order your pizza over the phone, go online, or stop by to place a takeout order.

First, start by selecting from one of our handmade crusts, like our hand-tossed crust that's packed with buttery flavor, a crispy thin crust, a pan crust featuring two delicious layers of cheese, or even a gluten-free pizza crust! Next, pick your sauce and load up on your favorite, most delish toppings. Whether you're a serious fan of mushrooms and spinach or love spicy pepperoni and tangy asiago cheese, your pizza dreams can come true at your local Domino's.

With over 34 million different ways to make a single Domino's pizza, you can be sure we've got a slice for any taste. Build your own pizza however you want or choose from one of our beloved specialty pizzas, like the popular Wisconsin 6 Cheese, Pacific Veggie, or ExtravaganZZa™, and have it delivered to your doorstep, super fast!

From Our Oven on Main St to Your Door: Patchogue Pizza Delivery

At your Domino's on Main St, we don't take pizza delivery lightly. In fact, we're so serious about it that we promise your pizza will arrive piping hot and freshly made, right from our oven to your door. Want to know what's happening with your order like, right now? Use our expertly engineered Domino's TrackerⓇ to follow along as your order is prepped, baked, checked for quality, and sent out our door for delivery... and in the meantime, try not to drool on your phone or computer.

Order online or call (631) 207-6800 now for the best pizza delivery in New York! Our delivery experts are fast and our pizzas are fresh. We promise!

Nearby Points of Interest


  • JFK


  • Brookhaven Memorial Hospital Medical Center