Start Your Order

All Deliveries Are Contactless.

XS App Module

All Deliveries are Contactless.

Domino's
421 Avenida De Mesilla
Las Cruces, NM 88005
Store Hours:
Mon-Thu
10:00 am to 12:00 am
Fri-Sat
10:00 am to 1:00 am
Sun
10:00 am to 12:00 am

NEW! Get Domino’s delivered to locations without a traditional address, like beaches, parks, stadium lots and more. Find a Hotspot Near You!

Domino’s National Coupons

Sorry, there are no offers available at this time. Check back soon!

SIGN UP FOR DOMINO'S EMAIL & TEXT OFFERS

Hot Local Deals

More About Domino’s Pizza

Domino's Pizza & Food Delivery at 421 Avenida De Mesilla in Las Cruces

Domino's delivers food in Las Cruces just the way you want it — hot, made to order, and undeniably delicious. Enjoy handcrafted pizza, pasta, and sandwiches, all baked to perfection for you. Order food online, by calling (575) 525-0900, or through the Domino's app!

Las Cruces Pizza Delivery Starts with Domino's on 421 Avenida De Mesilla

How do you combine two of your favorite things, Las Cruces and pizza? Next time your stomach rumbles for an oven-baked pizza that's worthy of a little drool, order Domino's at (575) 525-0900 for pizza delivery or takeout in Las Cruces. Domino's on Avenida de Mesilla has worked hard to master our recipe for delicious food and made-to-order pizza delivery in Las Cruces. Domino’s dedication to crafting and delivering high-quality pizza begins with selecting ingredients that are bursting with flavor and following a solid pizza-making process. Your Avenida de Mesilla Domino's starts cooking the moment you submit your order for pizza in Las Cruces. Your crunchy thin crust, hand-tossed, fluffy Brooklyn-style, or gluten-free pizza crust is prepped and doused in a sauce of your choosing. You can play it cool with a classic marinara or spice things up with Alfredo sauce, BBQ sauce, or garlic parmesan white sauce!

Next come your tasty toppings, the tidbits that make your pizza yours. Domino's long-time favorite pizza recipes deliver perfectly balanced flavor profiles for whatever makes your tastebuds happy. Crazy for Memphis BBQ Chicken? You got it. Love a good luau? Chow down on the Honolulu Hawaiian Pizza with sliced ham, smoked and crispy bacon, pineapple, and more! Prefer veggies to meat? Domino's has options for you, too. Get the Spinach & Feta Pizza or the Pacific Veggie! There are more than 34 million different ways to make a Domino's pizza, which means there's always a slice for every taste at your table!

You can design a one-of-a-kind pizza, too. The Pizza Builder puts you in the chef's shoes! Pick your pizza size, crust, sauce, amount of cheese, and any topping that catches your attention. There are no limits to what you can create. That's the beauty of pizza! Add on dipping sauces, bread twists, desserts, and drinks to round out your meal. Complete your order and get out the plates. It's okay if your mouth literally starts watering. Deliciousness is about to be ready for delivery or takeout in Las Cruces!

More Than Pizza on Avenida de Mesilla: Pasta, Sandwich & Wing Delivery, Too

Pizza lovers get it. They know Domino's on Avenida de Mesilla makes some of Las Cruces's best pizza. You can also get chicken wings, oven-baked sandwiches, pasta, and salads! Domino's started adding non-pizza items to the menu in 2008 and has grown to be one of the largest sandwich delivery restaurants in Las Cruces. Try Domino's oven-baked Philly Cheese Steak, Mediterranean Veggie, or Chicken Bacon Ranch sandwich and you'll see why Domino's sandwiches are so popular! They added Chocolate Lava Crunch Cake and baked pasta in 2009, plus a brand-new pizza recipe for crust, cheese, and sauce. The year 2011 brought chicken wings, plus more sugary goodness like Domino's decadent Marbled Cookie Brownie™. Go with Domino's at 421 Avenida De Mesilla if you want satisfying food delivery in Las Cruces. Your nearby Domino's on Avenida de Mesilla can't wait to satisfy your cravings with a handcrafted pizza, sandwich, salad, or bowl of pasta!

Get Las Cruces Pizza Delivery Anywhere You Are From Domino's on Avenida de Mesilla

Domino's is determined to be the go-to pizza delivery company, not only in Las Cruces, and every little thing that they do supports that commitment. Once your pizza, sandwich, or pasta leaves 421 Avenida De Mesilla, the Domino's TrackerⓇ will let you know! You can track your order right to your front door or somewhere else if you're not at home. (Wait, what?!) Yes! You can enjoy hot and delicious pizza delivery in Las Cruces even if you're not at home! Domino's Delivery Hotspots® mean you can have Domino's food delivered wherever you like to hang out in Las Cruces — beach, park, sports arena, or music venue. Just place your order online, select Delivery Hotspot, and allow Dominos.com to access your location. Find the closest Domino's Hotspot® and finish your order. We'll give you instructions from there, so all you have to do is enjoy every bite of your food!

Ready to Really Fall in Love with Domino's Pizza on Avenida de Mesilla?

When you open your Domino's pizza box, you want to know you're about to enjoy a handcrafted pizza that was made just for you, one with a perfectly baked crust, layers of melted cheese, and plenty of yummy vegetables and savory meats. It feels good to know you're getting more than that, though. Sign up for Domino's Piece of the Pie Rewards® and get ready to earn points towards a free pizza when you order. You'll also get access to special member pizza discounts and promotions! But if you don't do the whole "program" thing, that's alright, too. Everyone deserves to save money. That's why in addition to hot, yummy pizza, Domino's offers budget-winning Las Cruces pizza coupons. Call your Las Cruces Domino's pizza restaurant at (575) 525-0900 for current pizza deals and Las Cruces coupons. Pick from a combo deal, mix and match deal, carryout offer, and more! You never know what type of pizza coupon your local store will offer. When it comes to pizza places in Las Cruces, Domino's on Avenida de Mesilla is the place to go if you want to save money AND get tasty food just the way you like. So, what are you waiting for? Order finger-licking wings, sandwiches, pizza, or pasta today! Domino's pizza store at 421 Avenida De Mesilla offers both carryout and delivery in Las Cruces!

Start Your Order

Locations Nearby

Domino's
1763 E University
Las Cruces, NM 88001
Get Directions (575) 522-7700
Hours:
Sun-Thu:
10:00 am to 12:00 am
Fri:
10:00 am to 1:00 am
Sat:
10:00 am to 1:00 am
View Details
Domino's
3125 N Main St
Las Cruces, NM 88001
Get Directions (575) 528-0900
Hours:
Sun-Thu:
10:00 am to 12:00 am
Fri:
10:00 am to 1:00 am
Sat:
10:00 am to 1:00 am
View Details
Domino's
3090 N Roadrunner Pkwy
Las Cruces, NM 88011
Get Directions (575) 521-3030
Hours:
Sun-Thu:
10:00 am to 12:00 am
Fri:
10:00 am to 1:00 am
Sat:
10:00 am to 1:00 am
View Details
Domino's
5995 Bataan Memorial West
Las Cruces, NM 88012
Get Directions (575) 448-3030
Hours:
Sun-Thu:
10:00 am to 12:00 am
Fri:
10:00 am to 1:00 am
Sat:
10:00 am to 1:00 am
View Details

Get The Domino's Pizza App