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Domino's
105 South Main Street
Salem, MO 65560
Store Hours:
Mon-Thu
10:30 am to 10:29 pm
Fri-Sat
10:30 am to 11:29 pm
Sun
10:30 am to 10:29 pm

Domino's Carside Delivery is contact-free carry out. Find a location near you that carries your order right to your car - keeping you and our employees safe, one order at a time!

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More About Domino’s Pizza

Domino's Food & Pizza Delivery at 105 South Main Street in Salem

Craving something that's crispy-crunchy or salty-sweet? Get it from Domino's on Main St in Salem! Order delicious pizzas, chocolatey desserts, and more. Your local Domino's pizza place in Salem delivers your favorite foods. Order online, through the Domino's app, or call 573-453-2999 now!

Domino's on Main St — You Deserve the Best Pizza Delivery in Salem, MO

Salem, MO is an awesome place to live, and it deserves awesome pizza. Next time your stomach rumbles for a hot slice of ooey-gooey, crispy-crunchy pizza, call Domino's at 573-453-2999 for pizza takeout, carryout or delivery in Salem. Domino's on Main St has worked hard to fine tune our formula for taste bud-loving food and made-to-order pizza delivery in Salem. Domino's pledge to cooking and delivering made-to-order pizza starts with the ingredients and a tried and true pizza-making process. As soon as you place your order for Salem pizza carryout or delivery, your local Domino's on Main St starts cooking. Your hand-tossed, gluten-free, crunchy thin crust, or Brooklyn-style pizza crust is prepared and smothered in whatever sauce you choose. You can play it cool with a traditional marinara or kick things up a notch with BBQ sauce, garlic parmesan white sauce, or Alfredo sauce!

Then it's time for the toppings, the tidbits that define your pizza's taste. Domino's chef-inspired pizzas offer delectably balanced flavor combinations for whatever makes your tastebuds happy. Kookoo for Memphis BBQ Chicken? Sure thing! Prefer a little pineapple on your pizza? Try the Honolulu Hawaiian Pizza with the perfect blend of provolone and 100% real mozzarella, plus ham, pineapple, and bacon! Are you a vegetarian? There's a Domino's pizza for every veggie lover. Get the Spinach & Feta Pizza or the Pacific Veggie! There are more than 34 million different ways to make a Domino's pizza, which means there's always a slice for every taste at your table!

You can also create your own pizza recipe on the fly. The Pizza Builder lets you select every part of your pizza. Pick your pizza size, crust, sauce, amount of cheese, and however many toppings you want. The possibilities are endless. That's the beauty of pizza! Add desserts, bread twists, dipping sauces, and drinks to make it a complete meal. Wrap up your order and get ready. It's normal to drool a little bit. A box full of deliciousness is about to be ready for takeout or delivery in Salem!

Crave More? Order Sandwiches, Wings, or Pasta at 105 South Main Street

Foodies know: Domino's on Main St delivers more than some of the best pizza in Salem. You can also order salads, chicken wings, pasta, and oven-baked sandwiches! In 2008, Domino's began complementing the menu with non-pizza items and since then, has gradually become one of the biggest sandwich delivery places in Salem. Take a bite out of Domino's oven-baked Buffalo Chicken, Chicken Bacon Ranch, or Mediterannean Veggie sandwich and you'll see what all the fuss is about! They added Chocolate Lava Crunch Cake and baked pasta in 2009, in addition to a fresh pizza recipe for sauce, crust, and cheese. Chicken wings came in 2011, plus dreamy desserts like Domino's indulgent Marbled Cookie Brownie™. Go with Domino's at 105 South Main Street if you want satisfying food delivery in Salem. Your nearby Domino's on Main St can't wait to curb your hunger with a colorful salad, handcrafted pasta, pizza, or sandwich!

Domino's Pizza Delivery, Takeout, & More

Domino's is on a mission to be the go-to pizza delivery company, in Salem and beyond, and everything they do reflects this commitment. As soon as your pasta, pizza, or sandwich leaves the restaurant at 105 South Main Street, the Domino's TrackerⓇ will notify you. Track your order right up to your doorstep or somewhere else entirely if you're out having fun. Yup, you heard us. You don't have to be at your house or apartment to enjoy pizza delivery in Salem, MO! Thanks to Domino's Delivery Hotspots® you can have your favorite Domino's dishes delivered almost anywhere in Salem — park, beach, lake, sports field, or music festival. Just submit an order online, click on Delivery Hotspot, and grant Dominos.com access to your location. Find the closest Domino's Hotspot® and finish your order. We'll give you instructions from there, so all you have to do is enjoy every bite of your food! You can also have your favorite Domino's dishes delivered right to your car with our Domino’s Carside Delivery™. It's carryout, delivered. Place your carryout order as you normally would and head our way. When you arrive, a ready-to-go team member will bring your order out and put it in your vehicle. It's totally contact-free and totally smart.

Domino's Pizza Deals on Main St?

When you open your Domino's pizza box, you want to know you're about to enjoy a handcrafted pizza that was made just for you, one with a lightly toasted crust, oodles of melted cheese, and plenty of savory meats and delicious vegetables. It feels good to know you're getting more than that, though. Join Domino's Piece of the Pie Rewards® and start earning points towards a free pizza when you order. You'll also get access to special member pizza offers and promos! But you don't have to join a program to win big. Every pizza fanatic deserves to have a little more cash in their pocket. That's why on top of crave-worthy pizza, Domino's cooks up some pretty awesome pizza coupons in Salem. Call your Main St Domino's pizza restaurant at 573-453-2999 to learn more about current pizza deals and Salem coupons. Pick from a mix and match deal, combo deal, carryout deal, and more! Your local store's pizza offers are updated regularly. When it comes to pizza places in Salem, Domino's on Main St is the place to go if you want to save money AND get tasty food just the way you like. So, is it time to turn your hunger into happiness? Order drool-inducing chicken, pizza, pasta, or sandwiches today! Domino's pizza store at 105 South Main Street offers both carryout and delivery in Salem!

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