Earn points toward Free Pizza with Piece of the Pie Rewards

Domino's Pizza Locations

FREE COUPONS Sign up and never miss a deal!

Exclusive Online Offers

More About Your Indianapolis Domino's

Get Faster, Fresher Pizza in 46221

When you're craving a heavenly slice of cheesy, meaty, veggie-loaded goodness, we know your tastebuds don't want just any old pizza in 46221. You want a heavenly pizza topped with a robust tomato sauce, perfectly sliced bits of pepperoni, generous piles of mozzarella and parmesan, and a golden-brown crust that's both crispy and chewy. You want a slice of the perfect pizza. You want Domino's.

At Domino's in 46221, we make it quick and simple to get the fast, fresh pizza your hunger craves. Place a carryout order at the Domino's nearest you, order your pizza online, or give us a call!

Get started by picking one of our homemade crusts, including a fluffy, seasoned hand-tossed crust, a pan crust featuring two whopping layers of cheese, a crunchy thin crust, or even a gluten-free pizza crust! Then, choose your sauce and your favorite pizza toppings. Whether you're a freak for sausage and mushrooms or love sweet pineapple and tangy feta cheese, your local Domino's has it all.

There are more than 34 million ways to make a single Domino's pizza, which means you can be sure we've got a slice that suits your tastes. No matter how unique they are! Build your own pizza from scratch or choose from one of our specialty pizzas, like the popular MeatZZa™, Honolulu Hawaiian, or Memphis BBQ Chicken, and have it delivered to your door today, fast!

Like A Butler, But For Pizza: 46221 Pizza Delivery

At your Domino's in 46221, we don't take pizza delivery lightly. We guarantee that your pizza will arrive at your doorstep hot and fresh, straight from our oven. Stay up to date with the status of your order using our custom made TrackerⓇ. Enter in your phone number online and follow the progress of your pizza order from the moment you place it until it arrives at your door... and in the meantime, try not to drool on your phone or computer.

Your Tastebuds Want Pizza Takeout in 46221

We deliver pizza pretty darn fast, but we're also rockstars when it comes to lightning fast pizza takeout in 46221. Feel free to order from our pizza menu or take home something more! Make your tastebuds happy with one of our handcrafted sandwiches, oven-baked pastas, bread bites, salads, and a dangerously sweet helping of dessert. You can't go wrong with an order of Domino's Marbled Cookie Brownie™, Cinna StixⓇ, or Chocolate Lava Crunch Cake.

With over 12,000 locations in 80 plus countries, we know customer service and we know quality. We make it our mission to be the best pizza delivery company in Indianapolis, and everything we do reflects this commitment. You'll witness it in the way our delivery drivers take care of your order and you'll taste it in every bite of pizza you eat. Order online, call your nearest Domino's restaurant in 46221, or use our free smartphone app for hot, fast, and delicious pizza carryout and delivery today! We aren't any old 46221 pizza restaurant. We're your go-to pizza place in 46221!