Domino's Pizza - Salem

1340 W Main St

Salem, Illinois 62881 | (618) 548-6600
  • Mon-Thu: 10:30 am to 11 pm
  • Fri-Sat: 10:30 am to 12 am
  • Sun: 10:30 am to 11 pm
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More About Domino's on Main St

Spicy, Sweet or Savory: Get Pizza at 1340 W Main St

When you've got a hankering for a cheese-loaded slice of mouthwatering pizza, we know you're craving the best pizza in Salem. You want a heavenly pizza topped with a robust tomato sauce, generous heaps of mozzarella, expertly diced pepperoni, and a golden crust that's simultaneously chewy and crispy. You want a pizza that's hands down, undeniably delicious. You want Domino's.

At Domino's on Main St, it's never been easier to get the fast and delicious pizza your stomach is grumbling for! Order your pizza online or by calling (618) 548-6600, or stop by and place a takeout order in person.

Start by choosing from one of our handmade crusts, including a fluffy hand-tossed crust loaded with buttery flavor, a pan crust featuring two whopping layers of cheese, a crunchy thin crust, or even a gluten-free pizza crust! And next, select your sauce and start loading up on toppings. Pick as many or as few as you want! Whether you can't get enough grilled chicken and roasted veggies or you adore a savory variety of banana peppers, mushrooms, and pepperoni, you can make your dreams come true at your local Domino's!

We've got slices to suit any taste. How do we know? Because there are more than 34 million ways to craft a single Domino's pizza. Build your own pizza from scratch or choose from one of our specialty pizzas, like the popular Honolulu Hawaiian, Philly Cheese Steak, or Memphis BBQ Chicken, and have it delivered fresh and hot to your door, today!

Like A Butler, But For Pizza: Salem Pizza Delivery Near Main St

Order from your on Main St Domino's and you'll see—we're pretty serious folks when it comes to pizza delivery. In fact, we promise your pizza will arrive hot and fresh at your door, right out of our oven. Want to see how fast we can deliver? After you place your order, use our patented TrackerⓇ to stay up to date on the status of your pizza order. Follow it from the moment the sauce is added to the second it leaves our door for delivery... and in the meantime, try not to drool on your phone or computer.

Order online or call (618) 548-6600 now for the best pizza delivery in Illinois! Our delivery experts are fast and our pizzas are fresh. We promise!