Domino's Pizza - Port St Lucie

10642 S US Highway 1

Port St Lucie, Florida 34952 | (772) 335-0333
  • Mon-Thu: 10:30 am to 12 am
  • Fri-Sat: 10:30 am to 1 am
  • Sun: 10:30 am to 12 am
Get Directions

FREE COUPONS Sign up and never miss a deal!

Pizza Coupons Near You

Exclusive Online Offers

More About Domino's on US Highway 1

Destination? Delicious Pizza at 10642 S US Highway 1

When you're craving a mouthwatering slice of cheesy, meaty goodness, we know you're not craving just any old pizza in Port St Lucie. You want a heavenly pizza topped with a robust tomato sauce, generous heaps of mozzarella, expertly diced pepperoni, and a golden-brown crust that's crunchy, crispy, and chewy—all at the same time. You want a pizza that's hands down, undeniably delicious. You want Domino's.

At Domino's on US Highway 1, we make it easy to get exactly what you want: pizza that's fast and fresh. Walk in to place a takeout order, order your pizza online, or give us a call at (772) 335-0333!

Get started by selecting your favorite crust. Choose from a hand-tossed crust that's overflowing with buttery flavor, a gluten-free crust, a crunchy thin crust, or a pan pizza crust that's loaded with two layers of melted cheese! And next, select your sauce and start loading up on toppings. Pick as many or as few as you want! Whether you want to combine sausage, bacon, salami and green peppers, or stick to a blend of cheddar, mozzarella, feta, and asiago cheese, your pizza dreams can come true at your local Domino's.

With millions of different ways to craft a single Domino's pizza (yes, we said millions and we mean it), you can be sure we have a slice that suits your tastes. Build your own pizza however you want or choose from one of our beloved specialty pizzas, like the ever popular Buffalo Chicken, Pacific Veggie, or Ultimate Pepperoni and have it delivered hot and fresh to your doorstep, fast!

Fast Pizza Delivery on US Highway 1 in Port St Lucie

Here at your Domino's on US Highway 1, we're serious about pizza delivery. In fact, we're so serious about it that we promise your pizza will arrive piping hot and freshly made, right from our oven to your door. Can't wait for your pie to arrive? Use our patented Pizza TrackerⓇ system and follow your pizza order as it's prepped, baked, and headed out the door for delivery... and try not to drool on your phone or computer in the meantime.

Call (772) 335-0333 or order pizza delivery online now! Why keep your hunger waiting any longer?