Domino's Pizza - Vestavia Hills

5291 US Highway 280

Vestavia Hills, Alabama 35242 | 205-408-8100
  • Mon-Thu: 10 am to 12 am
  • Fri-Sat: 10 am to 1 am
  • Sun: 10 am to 12 am
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More About Domino's on Highway 280

Get Faster, Fresher Pizza at 5291 US Highway 280

When your stomach starts talkin' and your tastebuds start tinglin' for a classic slice of meaty, cheesy goodness, we know you're not craving any old pizza in Vestavia Hills You're looking for a flavorful pizza with a freshly made tomato sauce, a hearty blend of mozzarella and parmesan, expertly diced bits of pepperoni, and a golden crust that's simultaneously chewy and crispy. You want only the best pizza. You want Domino's.

At Domino's on Highway 280, we make it quick and simple to get the fast, fresh pizza your hunger craves. Call 205-408-8100 to order your pizza over the phone, go online, or stop by to place a takeout order.

Start by choosing from one of our handmade crusts, including a fluffy hand-tossed crust loaded with buttery flavor, a pan crust featuring two huge layers of cheese, a crispy thin crust, or a gluten-free pizza crust! Next, pick your sauce and start piling on your favorite toppings. Whether you can't get enough grilled chicken and roasted veggies or you adore a savory variety of banana peppers, mushrooms, and pepperoni, your pizza dreams can come true at your local Domino's.

With millions of different ways to craft a single Domino's pizza (yes, we said millions and we mean it), you can be sure we have a slice that suits your tastes. Build your own pizza from scratch or choose from one of our specialty pizzas, like the popular Spinach and Feta, Cali Chicken Bacon Ranch, or MeatZZa™, and have it delivered to your doorstep, today!

From Our Oven on Highway 280 to Your Door: Vestavia Hills Pizza Delivery

At your Domino's on Highway 280, we take pizza delivery pretty seriously. In fact, we'll make you a promise. We guarantee that your pizza will arrive hot and fresh, right from our toasty oven to your doorstep. Stay up to date with the status of your order using our custom made TrackerⓇ. Enter in your phone number online and follow the progress of your pizza order from the moment you place it until it arrives at your door... and try to keep your drool from falling onto your keyboard or phone in the meantime.

Order online or call 205-408-8100 now for pizza delivery near you. Our delivery experts are fast and our pizzas are fresh, just the way you like it!